First of all, I am sorry to hear this man, let me tell you some things that work for me while hunting and mining. I hunt and mine at the same time when I do big mobs. Also I mine unamped and do 100 bomb runs on my 3 fast-spawn zones per day. Took me many bombs to find them. I hunt when I have time(usually at the office lol) and do 20k ammo runs with 14k on korss400 and 6k on justymk2(I like the skill flow-and those are things I can only afford)
Now, I sometimes dont global on a day, but this only happens when I play very small, like 1-2 hrs. If you make only a single run on an area, you leave the global to pure chance. Globalling regularly is persistance in my opinion. Killed the bad spawn? you were unlucky. But logging out is equal to big loss then. You must try another run and see things may differ. It doesnt change? Then change mob. Bad again? I log out for that day and open a beer
You can understand what I will say next if you are an old player:The loot screen in times when you get back-to-back globals or profitable runs are not the same when you get bad loots right? Lots of no loots(attention here!),30-40 ammo and lots of 1 oil in loot window? 30-40 animal hides instead of 100+? then you may hit a big one(%10 chance) or lose big(%90). What you can do:
1-If you are camping that mob and looking for an item, you may shoot those spawn and pray the next spawn after them may be better
2-Change mob
3-Other
If you have peds, I say camp one mob and camp them in a fast spawn area, there is no need to re-explore America! Ithaca for Trox-Fury for Feff-Nymph for Argo, etc. You see in the long run things might get better.
Good luck